K.A. Lidke Lab

K.A. Lidke Laboratory

Optical and analysis methods for measuring the organization, dynamics, and interactions of proteins in living cells.

Datasets

Fast single-particle tracking of membrane proteins with super-resolution imaging of actin nanodomains

Correlative measurements combining fast single-particle tracking of IgE and GPI-anchored membrane proteins with single-molecule super-resolution images of the cortical actin cytoskeleton in RBL mast cells. HDF5 and MATLAB files are organized by condition (IgE / GPI × treated / untreated), with brightfield–IR images for registration. Published as a data descriptor in Scientific Data.
Mazloom-Farsibaf H, Kanagy WK, Lidke DS, Lidke KA. Scientific Data 12, 562 (2025) · data on Zenodo

Supporting data: sequential super-resolution imaging using DNA strand displacement

Data behind the sequential super-resolution method: strand-displacement kinetics and residual cross-talk measurements after invader treatment, together with image stacks from six rounds of sequential super-resolution imaging of subcellular structures in HeLa cells. Deposited in the UNM Digital Repository.
Pallikkuth S, Martin C, Farzam F, Edwards JS, Lakin MR, Lidke DS, Lidke KA. UNM Digital Repository (2018) · paper: PLoS ONE 13(8), e0203291